Description

Acetyl Chloride-13C2 CAS NO 89186-79-8 is a stable isotope-labeled derivative of acetyl chloride, where both carbon atoms are the carbon-13 isotope. This compound is essential for advanced analytical chemistry, providing a critical internal standard for precise quantification and metabolic pathway elucidation in mass spectrometry. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and environmental tracer analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses to ensure accuracy in drug and metabolite quantification.
• Metabolic Pathway Tracing: Enables the tracking of acetyl group incorporation in biochemical studies to understand metabolic fluxes and mechanisms.
• Pharmaceutical Research & Development: Critical for the synthesis of isotopically labeled drug candidates and metabolites for preclinical and clinical studies.
• Proteomics and Protein Acetylation Studies: Serves as a reagent for introducing stable isotope labels to study post-translational modifications like lysine acetylation.
• NMR Spectroscopy: Used as a labeled starting material or reagent to synthesize compounds for nuclear magnetic resonance studies, enhancing signal detection.
• Environmental Fate Studies: Applied as a tracer to study the environmental degradation and transformation pathways of acetyl-containing compounds.

Basic Information

Item	Details
Product Name	Acetyl Chloride-13C2
CAS No.	89186-79-8
Molecular Formula	13C2H3ClO
Molecular Weight	80.48 g/mol (approx.)
Synonyms	Acetic-13C2 chloride; Ethanoyl-13C2 chloride; [13C2]-Acetyl chloride; 13C2-Labeled acetyl chloride; 2,2-13C2-Acetyl chloride; Isotopic acetyl chloride; Carbon-13 labeled acetyl chloride; Acetyl chloride (13C2)
EINECS	Contact for details

Quality Control

Our Acetyl Chloride-13C2 is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity by GC or NMR, and identity confirmation. We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and strong acid/organic solvent nature, store in a cool, well-ventilated place, ideally at 2-8°C for extended stability. The container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR/NMR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (GC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.