Description

4-Phenyl-1,2,3,4-tetrahydroisoquinoline is a versatile tetrahydroisoquinoline derivative, a privileged scaffold in medicinal chemistry and organic synthesis. This compound matters as a key chiral intermediate and building block for the development of novel pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of potential therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to introduce stereochemical complexity.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating complex molecules with specific optical and chemical properties.
• Academic & Industrial R&D: Fundamental research material for exploring new chemical reactions and developing novel synthetic methodologies.

Basic Information

Product Name	4-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS No.	89160-45-2
Molecular Formula	C₁₅H₁₅N
Molecular Weight	209.29 g/mol
Synonyms	4-Phenyl-1,2,3,4-tetrahydroisoquinoline; 4-Phenyl-1,2,3,4-tetrahydro-isoquinoline; 1,2,3,4-Tetrahydro-4-phenylisoquinoline; 4-Phenyl-THIQ; 4-Phenyl-1,2,3,4-THIQ; 4-Phenyl-3,4-dihydro-1(2H)-isoquinoline; 4-Phenyl-1,2,3,4-tetrahydro-isoquinoline (enantiomers); 4-Phenyl-1,2,3,4-tetrahydroisoquinoline (racemic)
EINECS	Contact for details

Quality Control

Our 4-Phenyl-1,2,3,4-tetrahydroisoquinoline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. For customers with specific purity requirements (e.g., >98%, >99%), custom synthesis and purification services are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Optical Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.