Description

5-Chloro-1-[3-(Trifluoromethyl)Benzyl]-1H-Indole-2,3-Dione is a high-value, functionalized isatin derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity of the isatin scaffold combined with the chloro and trifluoromethylbenzyl substituents, enabling precise molecular construction for complex targets. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the indole-2,3-dione core.
• Organic Synthesis: Serves as a versatile precursor for heterocyclic chemistry, enabling the construction of complex fused-ring systems and spiro compounds.
• Material Science: Investigated as a monomer or functional component in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Utilized as a probe or scaffold in the design of enzyme inhibitors and molecular tools for biological research.

Basic Information

Product Name	5-Chloro-1-[3-(Trifluoromethyl)Benzyl]-1H-Indole-2,3-Dione
CAS No.	89159-26-2
Molecular Formula	C₁₆H₉ClF₃NO₂
Molecular Weight	339.70 g/mol
Synonyms	5-Chloro-1-[(3-trifluoromethyl)benzyl]isatin; 5-Chloro-1-(3-(trifluoromethyl)benzyl)indoline-2,3-dione; 1-(3-(Trifluoromethyl)benzyl)-5-chloroindoline-2,3-dione; 5-Chloro-1-(α,α,α-trifluoro-m-tolyl)isatin; 89159-26-2; 5-Chloro-1-(3-trifluoromethylbenzyl)isatin; 5-Chloro-1-(3-trifluoromethylbenzyl)-1H-indole-2,3-dione
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-[3-(Trifluoromethyl)Benzyl]-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to consistent quality and traceability supports your research and development needs from discovery to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.