Description

1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,[2S-(2-α-,3A-Bta-,7A-Bta-)]-(9Ci) is a high-purity, stereochemically defined indole derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and synthesis of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its rigid, polycyclic framework.
• Asymmetric Synthesis: Acts as a precursor or chiral auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Development: Employed in the discovery of new pesticides and herbicides where the indole core is a privileged structure.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new chemical space.
• Fine Chemical Synthesis: Incorporated into the multi-step synthesis of complex natural product analogs and specialty chemicals.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,[2S-(2-α-,3A-Bta-,7A-Bta-)]-(9Ci)
CAS No.	89105-38-4
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid; (2S,3aS,7aS)-2-Carboxyhexahydro-1H-indole; Hexahydro-1H-indole-2-carboxylic acid, (2S,3aS,7aS)-; L-Octahydroindole-2-carboxylic acid; (S,S,S)-2-Carboxyhexahydroindole; cis-Hexahydroindole-2-carboxylic acid; (2S,3aS,7aS)-Perhydroindole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,[2S-(2-α-,3A-Bta-,7A-Bta-)]-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profile is provided with every shipment to guarantee traceability and consistency for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.