Description

1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,(2-α-,3A-α-,7A-α-)-(9Ci) is a complex, stereochemically defined indole derivative that serves as a critical chiral building block in advanced organic synthesis. This compound matters for its rigid, fused-ring structure which provides a versatile scaffold for constructing pharmacologically active molecules with precise three-dimensional orientation. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of central nervous system (CNS) and anti-infective agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial configuration is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing complex chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and stereoselective chemistry.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its defined stereochemistry.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,(2-α-,3A-α-,7A-α-)-(9Ci)
CAS No.	89077-60-1
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2α,3aα,7aα)-Hexahydro-1H-indole-2-carboxylic acid; (2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid; 2-Carboxyhexahydroindole; cis-Hexahydroindole-2-carboxylic acid; (2S,3aR,7aR)-Octahydro-1H-indole-2-carboxylic acid; (2α,3aα,7aα)-2,3,3a,4,5,7a-Hexahydro-1H-indole-2-carboxylic acid; cis-Octahydroindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, hexahydro-, (2α,3aα,7aα)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your R&D and scale-up processes. Certificates of Analysis (COA) detailing identity, purity, and stereochemical integrity are available upon request. Our quality management system is designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.