Description

1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,(2-α-,3A-Bta-,7A-Bta-)-(9Ci) is a complex, stereochemically defined indole derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure, which provides a versatile scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific biological activity is required.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Natural Product Analog Synthesis: Employed in the total or semi-synthesis of complex natural products and their biologically active analogs.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,(2-α-,3A-Bta-,7A-Bta-)-(9Ci)
CAS No.	89077-54-3
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2α,3aβ,7aβ)-Hexahydro-1H-indole-2-carboxylic acid; (2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid; (2R,3aS,7aS)-2-Carboxyhexahydroindole; cis-Hexahydroindole-2-carboxylic acid; (2R,3aS,7aS)-Hexahydroindole-2-carboxylic acid; (2R,3aS,7aS)-1,2,3,3a,4,5,7,7a-Octahydroindole-2-carboxylic acid; (2R,3aS,7aS)-2-Carboxy-2,3,3a,4,5,7a-hexahydroindole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical purity, and identity. Our quality systems are designed to support cGMP and ISO guidelines for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.