Description

1-Bromo-4-Iodobutane is a versatile bifunctional alkyl halide building block, essential for organic synthesis and pharmaceutical research. Its distinct reactivity profile, featuring both bromine and iodine leaving groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as nucleophilic substitution reactions, cross-coupling, and the synthesis of heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Negishi) for carbon-carbon bond formation.
• Liquid Crystal & OLED Material Production: A precursor in the synthesis of advanced functional materials for electronic displays.
• Polymer Modification: Employed to introduce functional groups or chain-extend polymers.
• Organic Synthesis Reagent: A versatile reagent for nucleophilic substitution and alkylation reactions in research laboratories.
• Chemical Linker: Used to create spacers or linkers in bioconjugation and material science.

Basic Information

Product Name	1-Bromo-4-Iodobutane
CAS No.	89044-65-5
Molecular Formula	C4H8BrI
Molecular Weight	262.92 g/mol
Synonyms	4-Bromo-1-iodobutane; Butane, 1-bromo-4-iodo-; 1-Iodo-4-bromobutane; 4-Iodobutyl bromide; Tetramethylene bromoiodide; (4-Bromobutyl) iodide; 1,4-Dihalobutane (mixed halide); 4-Bromobutyl iodide
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Iodobutane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~2.1 g/mL
Boiling Point	~105-110°C / 15 mmHg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.