Description

N,n-Dimethylaniline-D3 (n-Methyl-D3) is a deuterated isotopologue of N,N-dimethylaniline, where three hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for applications requiring high chemical stability and minimal interference from background signals. It is an essential building block and analytical standard for researchers and manufacturers in the pharmaceutical and chemical synthesis sectors. The compound is particularly valuable for reaction mechanism studies, metabolic pathway tracing, and as an internal standard in mass spectrometry.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in GC-MS and LC-MS for the accurate quantification of N,N-dimethylaniline and related compounds.
• Pharmaceutical Research: Serves as a labeled precursor or intermediate in the synthesis of deuterated drug molecules for pharmacokinetic and metabolic stability studies.
• Mechanistic Studies: Employed as a tracer in chemical reaction studies to elucidate pathways and kinetics using spectroscopic techniques like NMR.
• Analytical Reference Material: Provides a certified reference material for calibrating instruments and validating analytical methods in quality control laboratories.
• Deuterated Solvent & Reagent: Acts as a specialty reagent in reactions where isotopic effects are being investigated or where reduced volatility is beneficial.

Basic Information

Product Name	N,n-Dimethylaniline-D3 (n-Methyl-D3)
CAS No.	88889-00-3
Molecular Formula	C8H8D3N
Molecular Weight	124.19 g/mol
Synonyms	N,N-Dimethylaniline-d3; (Dimethylamino-d3)benzene; N,N-Dimethyl-d3-aniline; N,N-Dimethylbenzenamine-d3; DMA-d3; Deuterated N,N-Dimethylaniline; Aniline, N,N-dimethyl-d3-; N-(Trideuteriomethyl)-N-methylaniline
EINECS	Contact for details

Quality Control

Our N,n-Dimethylaniline-D3 is produced under strict quality management protocols. Each batch is characterized by advanced analytical techniques including NMR, GC-MS, and HPLC to ensure isotopic purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and specific tests is provided with every shipment to guarantee reproducible results for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.