Description

Methyl 5-Acetylthiophene-3-Carboxylate is a high-purity, versatile heterocyclic building block and key synthetic intermediate. Its value lies in its bifunctional structure, featuring both an acetyl and an ester group on a thiophene core, enabling diverse chemical transformations for advanced synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active ingredients and functional organic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging the thiophene moiety for biological activity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), semiconductors, and sensors.
• Chemical Research & Development: Employed in academic and industrial R&D for heterocyclic chemistry, methodology development, and library synthesis for high-throughput screening.
• Ligand & Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and coordination chemistry.
• Fine Chemical Production: Acts as an intermediate in the multi-step synthesis of complex flavors, fragrances, and other specialty chemicals.

Basic Information

Product Name	Methyl 5-Acetylthiophene-3-Carboxylate
CAS No.	88770-21-2
Molecular Formula	C8H8O3S
Molecular Weight	184.21 g/mol
Synonyms	Methyl 5-acetyl-3-thiophenecarboxylate; 5-Acetyl-3-thiophenecarboxylic acid methyl ester; 3-(Methoxycarbonyl)-5-acetylthiophene; 5-Acetylthiophene-3-carboxylic acid methyl ester; Methyl 5-acetylthiophene-3-carboxylate; 3-Carbomethoxy-5-acetylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 5-Acetylthiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in research and scale-up synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.