Description

Methyl 5-Bromothiophene-3-Carboxylate is a high-purity brominated thiophene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive handle for further functionalization, enabling the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the thiophene core for bioactivity.
• Material Science Research: Serves as a precursor for conjugated polymers and organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis and Scale-up: Available for contract research organizations (CROs) and chemical companies requiring reliable, high-quality building blocks for custom synthesis projects.

Basic Information

Product Name	Methyl 5-Bromothiophene-3-Carboxylate
CAS No.	88770-19-8
Molecular Formula	C7H5BrO2S
Molecular Weight	233.08 g/mol
Synonyms	5-Bromo-3-thiophenecarboxylic acid methyl ester; Methyl 5-bromo-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 5-bromo-, methyl ester; 5-Bromothiophene-3-carboxylic acid methyl ester; Methyl 5-bromothiophene-3-carboxylate; 88770-19-8; 5-Bromo-3-methoxycarbonylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.