Description

Methyl 4-Chlorothiophene-3-Carboxylate is a high-purity organic building block and heterocyclic intermediate of significant commercial importance. Its value lies in its versatile reactivity, serving as a key precursor in the synthesis of complex molecules for advanced research and industrial applications. This compound is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical companies engaged in developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the thiophene moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or precursor for conducting polymers, organic semiconductors, and other electronic materials due to the thiophene core.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and functional group transformations to construct more complex heterocyclic systems.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and organic pigments.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial settings.

Basic Information

Product Name	Methyl 4-Chlorothiophene-3-Carboxylate
CAS No.	88770-14-3
Molecular Formula	C6H5ClO2S
Molecular Weight	176.62 g/mol
Synonyms	Methyl 4-chloro-3-thiophenecarboxylate; 4-Chloro-3-thiophenecarboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 4-chloro-, methyl ester; Methyl 4-chlorothiophene-3-carboxylic acid; 4-Chlorothiophene-3-carboxylic acid methyl ester; 3-Carbomethoxy-4-chlorothiophene
EINECS	Contact for details

Quality Control

Our Methyl 4-Chlorothiophene-3-Carboxylate is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.