Description

(1S)-1α-Amino-11-Bromo-1,2,7,8,13,13Bβ-Hexahydro[1,6,2]Oxathiazepino[2',3':1,2]Pyrido[3,4-B]Indol-10-Ol is a complex, high-purity heterocyclic compound featuring a unique fused ring system containing bromine and amino functional groups. This sophisticated molecular architecture makes it a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially within oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Oncology Drug Development: Its structural features make it a candidate for the development of novel kinase inhibitors or other targeted cancer therapies.
• CNS-Active Compound Synthesis: Potential intermediate in the research of new neurological and psychiatric medications due to its heterocyclic indole-based core.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of new chemical entities.

Basic Information

Product Name	(1S)-1α-Amino-11-Bromo-1,2,7,8,13,13Bβ-Hexahydro[1,6,2]Oxathiazepino[2',3':1,2]Pyrido[3,4-B]Indol-10-Ol
CAS No.	88704-50-1
Molecular Formula	C₁₇H₁₈BrN₃O₂S
Molecular Weight	408.31 g/mol
Synonyms	11-Bromo-1,2,7,8,13,13b-hexahydro[1,6,2]oxathiazepino[2',3':1,2]pyrido[3,4-b]indol-10-ol, (1S)-1-amino-; (1S)-1-Amino-11-bromo-1,2,7,8,13,13b-hexahydro[1,6,2]oxathiazepino[2',3':1,2]pyrido[3,4-b]indol-10-ol; (S)-1-Amino-11-bromo-1,2,7,8,13,13b-hexahydro[1,6,2]oxathiazepino[2',3':1,2]pyrido[3,4-b]indol-10-ol; Bromo-oxathiazepino-pyridoindol derivative; CAS 88704-50-1; Advanced Pharmaceutical Intermediate 88704-50-1
EINECS	Contact for details

Quality Control

Our (1S)-1α-Amino-11-Bromo-1,2,7,8,13,13Bβ-Hexahydro[1,6,2]Oxathiazepino[2',3':1,2]Pyrido[3,4-B]Indol-10-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.