Description

2-Acetyl-5-Cyanothiophene is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both acetyl and cyano substituents on a thiophene ring, makes it a versatile precursor for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its reactive functional groups.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the thiophene core contributes to color and stability properties.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	2-Acetyl-5-Cyanothiophene
CAS No.	88653-55-8
Molecular Formula	C7H5NOS
Molecular Weight	151.19 g/mol
Synonyms	1-(5-Cyanothiophen-2-yl)ethanone; 5-Cyanothiophene-2-yl methyl ketone; 2-Acetyl-5-cyanothiophene; 5-Cyano-2-acetylthiophene; 2-Acetylthiophene-5-carbonitrile; 1-(5-Cyano-2-thienyl)ethanone; Ethanone, 1-(5-cyano-2-thienyl)-; 88653-55-8
EINECS	Contact for details

Quality Control

Our 2-Acetyl-5-Cyanothiophene is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards and our quality systems are designed to support cGMP and ISO requirements for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.