Description

3,4-Dihydro-1-Isoquinolinecarboxylic Acid Ethyl Ester is a versatile heterocyclic building block of significant importance in synthetic organic chemistry. This compound serves as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for constructing isoquinoline-based scaffolds, which are prevalent in active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various alkaloid derivatives and potential drug candidates targeting neurological and cardiovascular systems.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the bioactive isoquinoline core.
• Organic Synthesis Building Block: Employed in cyclization reactions, annulations, and as a starting material for creating complex polycyclic structures in academic and industrial R&D.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Reference Standard: Supplied to analytical laboratories for method development, quality control, and regulatory compliance testing.

Basic Information

Product Name	3,4-Dihydro-1-Isoquinolinecarboxylic Acid Ethyl Ester
CAS No.	88612-00-4
Molecular Formula	C12H13NO2
Molecular Weight	203.24 g/mol
Synonyms	Ethyl 3,4-dihydro-1-isoquinolinecarboxylate; 1-Carbethoxy-3,4-dihydroisoquinoline; 1-Ethoxycarbonyl-3,4-dihydroisoquinoline; 3,4-Dihydroisoquinoline-1-carboxylic acid ethyl ester; Ethyl 1-isoquinolinecarboxylate, 3,4-dihydro-; 88612-00-4; 1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid ethyl ester (tautomeric form)
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1-Isoquinolinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.