Description

(+/-)-Benzyloxycarbonyl-α-Phosphonoglycine Trimethyl Ester is a protected phosphonoglycine derivative, a crucial building block in synthetic organic and medicinal chemistry. Its core value lies in enabling the controlled synthesis of phosphono amino acid analogs, which are key motifs in the development of enzyme inhibitors and bioactive compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require reliable, high-quality reagents for complex peptide and peptidomimetic synthesis.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing phosphonate-based protease and enzyme inhibitors with therapeutic potential.
• Peptidomimetic Research: Serves as a critical building block for creating stable phosphonopeptide analogs that mimic natural peptides.
• Agrochemical Development: Used in the research and synthesis of novel herbicidal or plant growth regulatory compounds containing phosphonate groups.
• Chemical Biology Probes: Employed in the design and construction of activity-based probes to study enzyme function and mechanism.
• Organophosphorus Chemistry: A versatile reagent for introducing the α-aminophosphonate moiety into more complex molecular architectures.
• Academic & R&D: Fundamental research tool in universities and contract research organizations for exploring new synthetic methodologies and bioactive molecules.

Basic Information

Product Name	(+/-)-Benzyloxycarbonyl-α-Phosphonoglycine Trimethyl Ester
CAS No.	88568-95-0
Molecular Formula	C14H20NO7P
Molecular Weight	345.29 g/mol
Synonyms	Z-α-Phosphonoglycine Trimethyl Ester; Cbz-α-Phosphonoglycine Trimethyl Ester; (Benzyloxycarbonylamino)(dimethoxyphosphoryl)acetic Acid Methyl Ester; (Z-Amino)(dimethoxyphosphoryl)acetic Acid Methyl Ester; α-[(Benzyloxycarbonyl)amino]benzeneacetic Acid α-(Dimethoxyphosphinyl) Methyl Ester; Phosphonoglycine, N-[(phenylmethoxy)carbonyl]-, Trimethyl Ester; N-Cbz-α-Aminophosphonoglycine Trimethyl Ester
EINECS	Contact for details

Quality Control

Our (+/-)-Benzyloxycarbonyl-α-Phosphonoglycine Trimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.