Description

3-Amino-5-Phenyl-Thiophene-2-Carboxylic Acid Ethyl Ester is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel pharmaceuticals and agrochemicals, offering a versatile scaffold for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its thiophene core.
• Material Science Research: Serves as a monomer or building block for developing novel organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and organic pigments.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for creating compound libraries in drug discovery programs.
• Custom Synthesis: The amino and ester functional groups provide handles for further derivatization, making it ideal for custom synthesis projects and scale-up services.

Basic Information

Product Name	3-Amino-5-Phenyl-Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	88534-50-3
Molecular Formula	C13H13NO2S
Molecular Weight	247.31 g/mol
Synonyms	Ethyl 3-Amino-5-phenylthiophene-2-carboxylate; 3-Amino-5-phenyl-2-thiophenecarboxylic acid ethyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-phenyl-, ethyl ester; 5-Phenyl-3-aminothiophene-2-carboxylic acid ethyl ester; AKOS BRN 0976; Ethyl 3-amino-5-phenyl-2-thiophenecarboxylate; 3-Amino-5-phenylthiophene-2-carboxylic acid ethyl ester; 88534-50-3
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Phenyl-Thiophene-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.