Description

3-(Chloromethyl)-1-Methyl-1H-Pyrazole Hydrochloride is a versatile and reactive heterocyclic building block, crucial for the synthesis of complex molecules in advanced chemical research and development. Its value lies in its bifunctional nature, offering both a reactive chloromethyl group and a pyrazole core, which serves as a key pharmacophore in medicinal chemistry. This compound is primarily needed by pharmaceutical R&D teams, agrochemical scientists, and specialty chemical manufacturers for constructing active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, including fungicides and herbicides, leveraging the pyrazole moiety's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, functionalized heterocyclic structures.

Basic Information

Product Name	3-(Chloromethyl)-1-Methyl-1H-Pyrazole Hydrochloride
CAS No.	88529-80-0
Molecular Formula	C5H8Cl2N2
Molecular Weight	167.03 g/mol
Synonyms	1-Methyl-3-(chloromethyl)-1H-pyrazole hydrochloride; 3-(Chloromethyl)-1-methylpyrazole hydrochloride; 1-Methyl-1H-pyrazole-3-methanol, hydrochloride, 3-(chloromethyl)-; 1-Methyl-3-chloromethylpyrazole HCl; Pyrazole, 3-(chloromethyl)-1-methyl-, hydrochloride; 1-Methyl-3-(chloromethyl)pyrazolium chloride
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-1-Methyl-1H-Pyrazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.