Description

6,7-Dihydroxycoumarin-4-Acetic Acid is a functionalized coumarin derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters for its role as a versatile synthetic intermediate and building block, particularly in the development of novel bioactive molecules and complex heterocyclic systems. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel anticoagulant, anti-inflammatory, and anticancer agents.
• Fluorescent Probe & Dye Precursor: Used in the development of chemosensors and fluorescent markers due to the inherent photophysical properties of the coumarin core.
• Agrochemical Research: Serves as a precursor for developing new generation herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Intermediate for producing complex heterocyclic compounds and specialty chemicals used in material science.
• Biochemical Research: Utilized in studying enzyme inhibition and as a scaffold for designing enzyme mimetics or inhibitors.
• Cosmetic Ingredient Development: Investigated for potential use in skin-care formulations leveraging its antioxidant properties derived from the dihydroxy structure.

Basic Information

Product Name	6,7-Dihydroxycoumarin-4-Acetic Acid
CAS No.	88404-14-2
Molecular Formula	C₁₁H₈O₆
Molecular Weight	236.18 g/mol
Synonyms	6,7-Dihydroxy-4-coumarinacetic acid; 2-(6,7-Dihydroxy-4-oxo-4H-chromen-2-yl)acetic acid; 6,7-Dihydroxy-2-carboxymethylchromone; 4-Carboxymethyl-6,7-dihydroxycoumarin; Esculetin-4-acetic acid; 6,7-Dihydroxycoumarinyl-4-acetic acid; 2-Acetic acid-6,7-dihydroxy-4-chromone
EINECS	Contact for details

Quality Control

Our 6,7-Dihydroxycoumarin-4-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.