Description

n-(6-Methylergolin-8β-Yl)-N',N'-Diethylurea is a synthetic ergoline derivative with a specific urea substitution. This compound is of significant interest in advanced pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) precursor. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents targeting neurological and cardiovascular systems.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex ergot alkaloid derivatives for drug discovery.
• Neurological Research: Used in preclinical studies investigating compounds with potential activity on serotonin and dopamine receptor systems.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Contract Research: Utilized in university and CRO settings for structure-activity relationship (SAR) studies and medicinal chemistry programs.
• API Development: Acts as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	n-(6-Methylergolin-8β-Yl)-N',N'-Diethylurea
CAS No.	88293-83-8
Molecular Formula	C₂₀H₂₈N₄O
Molecular Weight	340.47 g/mol
Synonyms	6-Methyl-8β-[(N',N'-diethylureido)methyl]ergoline; N-(6-Methylergolin-8-yl)-N',N'-diethylurea; 8β-[(N,N-Diethylcarbamoyl)amino]methyl]-6-methylergoline; 88293-83-8; LS-176087; Urea, N-(6-methylergolin-8.beta.-yl)-N',N'-diethyl-; Diethylurea derivative of 6-methylergoline
EINECS	Contact for details

Quality Control

Our n-(6-Methylergolin-8β-Yl)-N',N'-Diethylurea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.