Description

Notopterol is a bioactive furanocoumarin compound derived from the traditional medicinal plant *Notopterygium incisum*. This high-purity reference standard is essential for research and development, offering a reliable benchmark for analytical and pharmacological studies. It is primarily utilized by professionals in the pharmaceutical, nutraceutical, and phytochemical industries for quality control, method validation, and bioactivity screening.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification and quantification of Notopterol in herbal extracts and finished products.
• Bioactivity Research: Used in preclinical studies to investigate its anti-inflammatory, analgesic, and potential neuroprotective properties.
• Natural Product Isolation & Analysis: A key marker compound for the quality assessment and standardization of *Notopterygium* species (Qianghuo) in herbal medicine.
• Analytical Method Development: Employed to develop and validate HPLC, UPLC, and LC-MS methods for complex botanical matrices.
• Dietary Supplement Formulation: Acts as a reference for ensuring the potency and consistency of herbal supplement ingredients.
• Academic & Contract Research: A critical reagent for universities and CROs conducting phytochemical and pharmacological research.

Basic Information

Product Name	Notopterol
CAS No.	88206-46-6
Molecular Formula	C21H22O5
Molecular Weight	354.40 g/mol
Synonyms	Notopterol; (E)-3-[(2S,3R)-3-Hydroxy-3-methyl-4-(3-methylbut-2-en-1-yl)oxiran-2-yl]-2-(2-methylbut-3-en-2-yl)-2,3-dihydro-4H-furo[3,2-c]chromen-4-one; 6-(3,3-Dimethylallyl)-7-hydroxycoumarin; 7-Hydroxy-6-(3-methyl-2-butenyl)coumarin; Isoimperatorin (Note: Isoimperatorin is a closely related isomer, often referenced together)
EINECS	Contact for details

Quality Control

Our Notopterol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.