Description

4-Nitrophenyl Chloromethyl(Phenyl)Phosphinate is a specialized organophosphorus compound with a unique bifunctional structure, serving as a critical building block in advanced chemical synthesis. Its value lies in its dual reactivity, offering a chloromethyl group for alkylation and a phosphinate ester moiety for further functionalization, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel biologically active molecules, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, insecticides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized phosphinate-based ligands for metal catalysis.
• Polymer Modification: Employed to introduce phosphinate functional groups into polymer backbones to impart flame retardancy or metal-chelating properties.
• Chemical Biology Probes: Useful in constructing activity-based probes for studying phosphinate-interacting enzymes and biological pathways.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form carbon-phosphorus bonds.

Basic Information

Product Name	4-Nitrophenyl Chloromethyl(Phenyl)Phosphinate
CAS No.	88144-99-4
Molecular Formula	C13H11ClNO4P
Molecular Weight	311.66 g/mol
Synonyms	Chloromethyl(phenyl)phosphinic Acid 4-Nitrophenyl Ester; Phenyl(chloromethyl)phosphinic Acid 4-Nitrophenyl Ester; 4-Nitrophenyl Phenyl(chloromethyl)phosphinate; (4-Nitrophenoxy)(phenyl)(chloromethyl)phosphine Oxide; Phosphinic acid, P-(chloromethyl)-P-phenyl-, 4-nitrophenyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-Nitrophenyl Chloromethyl(Phenyl)Phosphinate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.