Description

4-Acetylthiophene-2-Carboxylic Acid is a versatile heterocyclic building block that combines a carboxylic acid and an acetyl group on a thiophene scaffold. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical chemists and agrochemical researchers for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as conductive polymers and organic semiconductors.
• Ligand and Catalyst Development: The carboxylic acid and acetyl functionalities allow for its use in designing novel ligands for metal catalysis and coordination chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating specialized chemical libraries.
• Fine Chemical Synthesis: An intermediate in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	4-Acetylthiophene-2-Carboxylic Acid
CAS No.	88105-23-1
Molecular Formula	C7H6O3S
Molecular Weight	170.19 g/mol
Synonyms	2-Thiophenecarboxylic acid, 4-acetyl-; 4-Acetyl-2-thiophenecarboxylic acid; 4-Acetylthiophene-2-carboxylic acid; 4-Acetyl-2-thiophene carboxylic acid; 4-Acetylthiophene-2-carboxylate; 4-Acetyl-2-carboxythiophene; 2-Carboxy-4-acetylthiophene; 88105-23-1
EINECS	Contact for details

Quality Control

Our 4-Acetylthiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.