Description

2-Thiophenecarboxylic Acid, 4-Iodo-, Methyl Ester is a high-purity iodinated thiophene derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both a thiophene ring and an iodine substituent, makes it an essential intermediate for constructing complex molecules with tailored electronic and pharmaceutical properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to the development of organic semiconductors.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and anti-infective therapies.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the thiophene moiety can contribute to specific biological activity.
• Material Science Precursor: Acts as a monomer or precursor in the synthesis of conjugated polymers and organic electronic materials for OLEDs, OFETs, and sensors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including those used in cross-coupling reactions facilitated by the reactive iodine handle.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological processes due to its potential for further functionalization.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in both university and corporate research laboratories.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 4-Iodo-, Methyl Ester
CAS No.	88105-20-8
Molecular Formula	C7H5IO2S
Molecular Weight	280.08 g/mol
Synonyms	Methyl 4-iodothiophene-2-carboxylate; 4-Iodothiophene-2-carboxylic Acid Methyl Ester; Methyl 4-iodo-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 4-iodo-, methyl ester; 4-Iodo-2-thiophenecarboxylic acid methyl ester; 4-Iodo-2-methoxycarbonylthiophene
EINECS	Contact for details

Quality Control

Every batch of 2-Thiophenecarboxylic Acid, 4-Iodo-, Methyl Ester is produced and tested under a strict quality management system to ensure consistency and reliability for your critical research and development work. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.