Description

(R)-1-Phosphono-3-Methyl-Butylamine CAS NO 88081-77-0 is a chiral, phosphorus-containing amino acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phosphonic acid group and a primary amine, makes it a valuable ligand and intermediate for creating complex molecules with specific stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the production of advanced, chiral herbicides, fungicides, and plant growth regulators.
• Catalyst & Ligand Development: Serves as a precursor for metal-complexing ligands in asymmetric catalysis and coordination chemistry.
• Biochemical Research: Utilized as a substrate analog or inhibitor in enzymatic studies, particularly those involving phosphonate metabolism.
• Material Science: Potential monomer or additive for creating functional polymers with specific chelating or surface-modifying properties.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability and bioactivity by mimicking phosphate esters.

Basic Information

Product Name	(R)-1-Phosphono-3-Methyl-Butylamine
CAS No.	88081-77-0
Molecular Formula	C5H14NO3P
Molecular Weight	167.14 g/mol
Synonyms	(R)-1-Amino-3-methylbutylphosphonic Acid; (R)-3-Methyl-1-aminobutylphosphonic Acid; (R)-HomoPhe(P) Phosphonic Acid Analogue; (R)-Phosphonoleucine; (R)-1-Phosphono-3-methylbutylamine; (R)-AMPB; (R)-1-Amino-3-methylbutyl-1-phosphonic Acid; (R)-HomoPhe(P)
EINECS	Contact for details

Quality Control

Our (R)-1-Phosphono-3-Methyl-Butylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.