Description

2-(Bromomethyl)-3-Thiophenecarboxylic Acid Methyl Ester is a versatile and reactive brominated thiophene derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an electrophilic bromomethyl group and an ester functionality, makes it an invaluable precursor for constructing complex heterocyclic systems and functionalized materials. This high-purity intermediate is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiophene core contributes to biological activity.
• Material Science & Organic Electronics: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and photovoltaic cells.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and organocatalysis.
• Chemical Research: A valuable reagent for methodology development and exploratory synthesis in academic and industrial R&D laboratories.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring a functionalized thiophene backbone.

Basic Information

Product Name	2-(Bromomethyl)-3-Thiophenecarboxylic Acid Methyl Ester
CAS No.	88048-78-6
Molecular Formula	C7H7BrO2S
Molecular Weight	235.10 g/mol
Synonyms	Methyl 2-(Bromomethyl)thiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 2-(bromomethyl)-, methyl ester; 2-Bromomethyl-3-methoxycarbonylthiophene; Methyl 3-Thiophenecarboxylate, 2-(bromomethyl)-; 2-Bromomethyl-3-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-3-Thiophenecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP and ISO standards guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.