Description

2-(Propyl-1,1-D2)Pentanoic-3,3-D2 Acid is a deuterium-labeled analog of 2-propylpentanoic acid, a branched-chain carboxylic acid. This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in LC-MS and GC-MS analyses for the accurate quantification of its non-deuterated counterpart or related metabolites.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of pharmaceutical compounds.
• Biomedical Research: Enables precise tracking and analysis of biochemical pathways and metabolic processes in in vitro and in vivo studies.
• Analytical Method Development and Validation: Provides a stable isotope-labeled standard to enhance the accuracy, precision, and reliability of bioanalytical assays.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities or degradation products during drug development.
• Chemical Synthesis Research: Acts as a labeled building block or intermediate for synthesizing more complex deuterated molecules for research purposes.

Basic Information

Item	Detail
Product Name	2-(Propyl-1,1-D2)Pentanoic-3,3-D2 Acid
CAS No.	87745-17-3
Molecular Formula	C8H12D4O2
Molecular Weight	148.25 g/mol (for deuterated form)
Synonyms	2-Propylpentanoic-3,3,1',1'-d4 Acid; Deuterated Valproic Acid (d4); 2-Propylvaleric-d4 Acid; Valproic-d4 Acid; D4-2-Propylpentanoic Acid; 2-(Propyl-1,1-d2)Valproic-3,3-d2 Acid; 2-Propylpentanoic Acid-d4
EINECS	Contact for details

Quality Control

Every batch of 2-(Propyl-1,1-D2)Pentanoic-3,3-D2 Acid is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity through rigorous analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.