Description

1H-Indole-2-Carboxylicacid,Octahydro-,(2R,3As,7Ar)-Rel-(9Ci) is a high-purity, stereochemically defined indole derivative, a key chiral building block in advanced organic synthesis. Its rigid, fused bicyclic structure and defined stereochemistry make it a valuable scaffold for constructing complex molecules with specific three-dimensional orientations. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients where precise spatial configuration is critical for biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used as a building block for developing new, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Investigated as a monomer or precursor for creating novel polymers with specific optical or electronic properties.
• Academic & Contract Research: A valuable reagent for methodological development in synthetic organic chemistry and stereoselective transformations.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,Octahydro-,(2R,3As,7Ar)-Rel-(9Ci)
CAS No.	87679-58-1
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2R,3aS,7aR)-Octahydro-1H-indole-2-carboxylic acid; rel-(2R,3aS,7aR)-Octahydroindole-2-carboxylic acid; (2R,3aS,7aR)-Octahydroindole-2-carboxylic acid; cis-Octahydroindole-2-carboxylic acid (stereospecific); 2-Carboxyhexahydropyrrolo[1,2-a]pyrazine-1(2H)-one (bridged bicyclic form); Perhydroindole-2-carboxylic acid; Proline-derived bicyclic amino acid; Chiral indoline-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-2-Carboxylicacid,Octahydro-,(2R,3As,7Ar)-Rel-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure compliance with stringent purity and stereochemical integrity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvent levels is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.