Description

1H-Indole-2-Carboxylicacid,Octahydro-,(2-α-,3A-α-,7A-α-)-(9Ci) is a high-purity, stereochemically defined indole derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure, which is essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific spatial orientation affects biological activity.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for enantioselective transformations.
• Academic & R&D: Serves as a valuable scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,Octahydro-,(2-α-,3A-α-,7A-α-)-(9Ci)
CAS No.	87679-20-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2α,3aα,7aα)-Octahydro-1H-indole-2-carboxylic acid; (2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid; (2α,3aα,7aα)-Octahydroindole-2-carboxylic acid; cis-Octahydroindole-2-carboxylic acid; cis-Oic; (2S,3aR,7aR)-Enantiomer (if applicable); Perhydroindole-2-carboxylic acid; Stereo-defined indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylicacid,Octahydro-,(2-α-,3A-α-,7A-α-)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.