Description

(2S)-2-Acetamido-3-(6-Hydroxy-1H-Indol-3-Yl)Propanoic Acid is a specialized chiral amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its indole and hydroxyl functional groups, which make it a versatile intermediate for constructing complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Research: Used as a modified amino acid residue for constructing non-natural peptides and peptidomimetics with enhanced stability or biological activity.
• Biochemical Tool Compound: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for related compounds.
• Academic & R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory filings in pharmaceutical manufacturing.

Basic Information

Product Name	(2S)-2-Acetamido-3-(6-Hydroxy-1H-Indol-3-Yl)Propanoic Acid
CAS No.	87667-59-2
Molecular Formula	C₁₃H₁₄N₂O₄
Molecular Weight	262.26 g/mol
Synonyms	N-Acetyl-6-hydroxytryptophan; L-N-Acetyl-6-hydroxytryptophan; (S)-2-Acetamido-3-(6-hydroxy-1H-indol-3-yl)propanoic acid; 6-Hydroxy-N-acetyl-L-tryptophan; 6-Hydroxy-L-Trp(Ac); 87667-59-2; N-Acetyl-6-hydroxy-L-tryptophan
EINECS	Contact for details

Quality Control

Our (2S)-2-Acetamido-3-(6-Hydroxy-1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.