Description

Ethyl [3As-(3Aalpha,4Beta,6Aalpha)]-Hexahydro-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Valerate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for the synthesis of specialized active pharmaceutical ingredients (APIs) and serves as a key building block in modern medicinal chemistry. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly those targeting complex biochemical pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a sophisticated building block for constructing novel molecular scaffolds in drug discovery and development programs.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Prodrug Development: Its functional groups make it suitable for creating targeted drug delivery systems and prodrug formulations.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in regulatory filings.

Basic Information

Product Name	Ethyl [3As-(3Aalpha,4Beta,6Aalpha)]-Hexahydro-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Valerate
CAS No.	87573-52-2
Molecular Formula	C13H19N3O3S
Molecular Weight	297.37 g/mol
Synonyms	Ethyl (3aR,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valerate; 1H-Thieno[3,4-d]imidazole-4-valeric acid, hexahydro-2-oxo-, ethyl ester, (3aS-(3aalpha,4beta,6aalpha))-; Biotin Ethyl Ester; D-Biotin Ethyl Ester; Vitamin H Ethyl Ester; (+)-Biotin Ethyl Ester; Ethyl D-Biotinate
EINECS	Contact for details

Quality Control

Our production of Ethyl [3As-(3Aalpha,4Beta,6Aalpha)]-Hexahydro-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Valerate adheres to stringent quality management systems, ensuring batch-to-batch consistency and traceability. The material is manufactured and tested to meet exacting standards suitable for pharmaceutical R&D and GMP applications. Comprehensive analytical testing, including chiral purity verification, is performed. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.