Description

Pentafluoroethane-D1 CAS NO 87458-21-7 is a deuterated isotopologue of pentafluoroethane (R-125), where one hydrogen atom is replaced by deuterium. This compound is a highly volatile, gaseous substance valued for its utility as a labeled standard in analytical chemistry and research. It is primarily required by pharmaceutical, environmental, and advanced materials research laboratories for use in mass spectrometry, NMR spectroscopy, and kinetic studies where isotopic tracing is essential.

Application

• Internal Standard for GC/MS and LC/MS Analysis: Used for the accurate quantification of pentafluoroethane and related compounds in environmental and biological samples.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated tracer or solvent component in nuclear magnetic resonance studies to elucidate molecular structures and reaction mechanisms.
• Kinetic Isotope Effect (KIE) Studies: Employed in fundamental chemical research to investigate reaction pathways and rates by comparing the behavior of the deuterated vs. non-deuterated molecule.
• Atmospheric and Environmental Research: Acts as a labeled reference material for tracking the fate and transport of fluorinated greenhouse gases.
• Pharmaceutical Metabolism Research: Utilized as a stable isotope-labeled analog in drug metabolism and pharmacokinetics (DMPK) studies.
• Calibration Standard for Analytical Instruments: Provides a known, high-purity reference for calibrating detectors sensitive to fluorinated compounds.

Basic Information

Product Name	Pentafluoroethane-D1
CAS No.	87458-21-7
Molecular Formula	C2HF5D
Molecular Weight	122.04 g/mol
Synonyms	Deutero-pentafluoroethane; R-125-d1; 1,1,1,2,2-Pentafluoro-2-deuteroethane; HFC-125-d1; Freon 125-d1; Pentafluoro(deuterio)ethane; Ethane, 1,1,1,2,2-pentafluoro-2-d1-
EINECS	Contact for details

Quality Control

Our Pentafluoroethane-D1 is produced and handled under strict quality protocols to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity by GC, and impurity profiles. We adhere to cGMP principles where applicable for research-grade materials.

Storage

Preserve in a tightly closed, appropriately rated cylinder or container in a cool, well-ventilated area. Due to its highly volatile and gaseous nature, store away from heat, sparks, and open flames. Protect from physical damage and direct sunlight. Keep container valve closed when not in use.

Specification

Item	Specification
Appearance	Colorless Gas
Identification (IR / NMR)	Conforms
Assay (GC)	≥ 99.0% (area%)
Isotopic Purity (D atom %)	≥ 98.0%
Water Content (KF)	≤ 100 ppm
Non-Volatile Residue	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.