Description

2-Butenoic Acid, 2-(Hydroxymethyl)-, ((1R,7Ar)-2,3,5,7A-Tetrahydro-1-(((2Z)-2-Methyl-1-Oxo-2-Butenyl)Oxy)-1H-Pyrrolizin-7-Yl)Methyl Ester, (2E)- is a complex organic ester with a defined stereochemistry, serving as a critical advanced intermediate in specialized chemical synthesis. Its value lies in its precise molecular architecture, which is essential for constructing sophisticated pharmacologically active compounds. This high-purity intermediate is primarily needed by research institutions and pharmaceutical development companies focused on creating novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research for new drug candidates.
• Chemical Research & Development: Used as a precursor in advanced organic synthesis for creating novel molecular structures with potential biological activity.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring specific stereochemical configurations.
• Biochemical Studies: May serve as a tool compound or a synthetic intermediate in biochemical pathway research and probe development.

Basic Information

Item	Details
Product Name	2-Butenoic Acid, 2-(Hydroxymethyl)-, ((1R,7Ar)-2,3,5,7A-Tetrahydro-1-(((2Z)-2-Methyl-1-Oxo-2-Butenyl)Oxy)-1H-Pyrrolizin-7-Yl)Methyl Ester, (2E)-
CAS No.	87392-67-4
Molecular Formula	C17H23NO5
Molecular Weight	321.37 g/mol
Synonyms	(2E)-2-(Hydroxymethyl)-2-butenoic acid ((1R,7aR)-2,3,5,7a-tetrahydro-1-{[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy}-1H-pyrrolizin-7-yl)methyl ester; (E)-2-(Hydroxymethyl)but-2-enoic acid (1R,7aR)-1-(((Z)-2-methylbut-2-enoyl)oxy)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-ylmethyl ester; A key retronecine ester derivative; Advanced pyrrolizidine alkaloid intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 2-(Hydroxymethyl)-, ((1R,7Ar)-2,3,5,7A-Tetrahydro-1-(((2Z)-2-Methyl-1-Oxo-2-Butenyl)Oxy)-1H-Pyrrolizin-7-Yl)Methyl Ester, (2E)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profiling, to ensure it meets the exacting standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from heat and incompatible materials. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.