Description

4-Chlorobenzoyl-D4 Chloride is a deuterated derivative of 4-chlorobenzoyl chloride, a key acylating agent and synthetic intermediate. This compound is specifically valued for its role in the preparation of isotopically labeled compounds, which are essential for advanced analytical and research applications. It is primarily utilized by pharmaceutical, agrochemical, and academic research sectors for applications in drug metabolism studies, analytical standards, and mechanistic research.

Application

• Synthesis of Deuterated Pharmaceutical Intermediates: Used as a building block for creating isotopically labeled active pharmaceutical ingredients (APIs) and metabolites.
• Internal Standards for Mass Spectrometry: Serves as a crucial precursor for developing quantitative internal standards in LC-MS and GC-MS analysis, enhancing accuracy in bioanalytical studies.
• Agrochemical Research: Employed in the synthesis of labeled agrochemicals for environmental fate and metabolism studies.
• Mechanistic Reaction Studies: Utilized in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms in organic chemistry.
• Material Science: Can be used in the synthesis of specialized polymers or liquid crystals where isotopic labeling is required for property analysis.

Basic Information

Product Name	4-Chlorobenzoyl-D4 Chloride
CAS No.	87367-51-9
Molecular Formula	C7D4Cl2O
Molecular Weight	177.04 g/mol
Synonyms	4-Chlorobenzoyl-d4 Chloride; p-Chlorobenzoyl-d4 Chloride; Benzoyl-d4 Chloride, 4-chloro-; Deutero-p-Chlorobenzoyl Chloride; (2,3,5,6-Tetradeutero-4-chlorophenyl)carbonyl Chloride; 4-Chlorobenzoyl Chloride-d4; 87367-51-9; p-Chlorobenzoyl-d4 acid chloride
EINECS	Contact for details

Quality Control

Our 4-Chlorobenzoyl-D4 Chloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ²H) and HPLC, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with water, strong acids, and bases. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.