Description

5-Oxo-1,2,3,5-Tetrahydro-Indolizine-8-Carboxylic Acid Methyl Ester is a high-value, heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical synthesis. Its unique fused indolizine structure makes it a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences sector seeking to develop novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct the indolizine core, a privileged scaffold found in many bioactive molecules.
• Agrochemical Research: Employed in the development of new pesticides and herbicides where the indolizine moiety can impart specific biological activity.
• Material Science Precursor: Investigated for the synthesis of advanced organic materials, including dyes and functional polymers.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	5-Oxo-1,2,3,5-Tetrahydro-Indolizine-8-Carboxylic Acid Methyl Ester
CAS No.	87286-02-0
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	Methyl 5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate; 8-Methoxycarbonyl-5-oxo-1,2,3,5-tetrahydroindolizine; 5-Oxo-2,3-dihydro-1H-indolizine-8-carboxylic acid methyl ester; 1,2,3,5-Tetrahydro-5-oxoindolizine-8-carboxylic acid methyl ester; Methyl 1,2,3,5-tetrahydro-5-oxoindolizine-8-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-Oxo-1,2,3,5-Tetrahydro-Indolizine-8-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, which is critical for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the exacting standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.