Description

Methyl 5,6,7,8-Tetrahydro-1-Indolizinecarboxylate CAS NO 87281-43-4 is a high-purity, advanced pharmaceutical intermediate belonging to the indolizine class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. This compound is essential for manufacturers and research institutions focused on developing novel therapeutic agents, including potential candidates in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of indolizine-based libraries for high-throughput screening and combinatorial chemistry.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Material Science: Investigated for the synthesis of specialty chemicals and functional organic materials.

Basic Information

Product Name	Methyl 5,6,7,8-Tetrahydro-1-Indolizinecarboxylate
CAS No.	87281-43-4
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	Methyl 5,6,7,8-tetrahydroindolizine-1-carboxylate; 1H-Indolizine-1-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester; Methyl 1-indolizinecarboxylate, 5,6,7,8-tetrahydro-; 87281-43-4; Methyl tetrahydroindolizine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5,6,7,8-Tetrahydro-1-Indolizinecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.