Description

4-(tert-Butyldimethylsilyl)-Oxy-1-Butanol is a valuable organosilicon-protected alcohol intermediate, widely recognized by its CAS number 87184-99-4. This compound is essential for synthetic chemists as it provides a robust protecting group for primary alcohols, enabling selective reactions in complex multi-step syntheses. It is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for sophisticated organic transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where alcohol protection is required.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require selective protection/deprotection strategies.
• Peptide Chemistry: Employed in the synthesis of peptide analogs and other biomolecules where sensitive functional groups must be shielded.
• Natural Product Synthesis: Facilitates the complex total synthesis of natural products by protecting hydroxyl groups during critical steps.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the development of specialty silicones and functional polymers.
• Organic Synthesis Research: A staple reagent in academic and industrial R&D laboratories for method development and exploratory chemistry.

Basic Information

Item	Detail
Product Name	4-(tert-Butyldimethylsilyl)-Oxy-1-Butanol
CAS No.	87184-99-4
Molecular Formula	C10H24O2Si
Molecular Weight	204.39 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]-1-butanol; 4-(TBDMS-Oxy)-1-Butanol; 4-Hydroxybutyl tert-butyldimethylsilyl ether; 1-Butanol, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 4-O-TBDMS-1-butanol; 4-(tert-Butyldimethylsiloxy)butan-1-ol; TBDMS-protected 4-hydroxybutanol
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyldimethylsilyl)-Oxy-1-Butanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.