Description

1,1-Bis(Trimethylsilyloxy)-3-Methyl-1,3-Butadiene is a specialized organosilicon reagent featuring a protected diene functionality. This compound is highly valued in organic synthesis for its role as a versatile building block in the construction of complex molecular frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise carbon-carbon bond formation.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex natural products and active pharmaceutical ingredients (APIs), particularly for Diels-Alder and other cycloaddition reactions.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides, leveraging its reactive diene system to create specific ring structures.
• Material Science Research: Used in the preparation of specialty polymers and advanced organic materials where the introduction of a silyl-protected diene unit is required.
• Organic Methodology Development: Serves as a model substrate in academic and industrial research for developing new catalytic and stereoselective synthetic transformations.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value fragrances, flavors, and other specialty chemicals.

Basic Information

Product Name	1,1-Bis(Trimethylsilyloxy)-3-Methyl-1,3-Butadiene
CAS No.	87121-05-9
Molecular Formula	C11H24O2Si2
Molecular Weight	244.48 g/mol
Synonyms	3-Methyl-1,1-bis(trimethylsiloxy)-1,3-butadiene; 1,3-Butadiene, 1,1-bis[(trimethylsilyl)oxy]-3-methyl-; 1,1-Bis(trimethylsiloxy)-3-methylbutadiene; TMS-protected 3-methyl-1,3-butadien-1-ol; Danishefsky's Diene (methyl-substituted variant); 3-Methyl-1-(trimethylsiloxy)-1-(trimethylsiloxy)-1,3-butadiene
EINECS	Contact for details

Quality Control

Our 1,1-Bis(Trimethylsilyloxy)-3-Methyl-1,3-Butadiene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.