Description

Benzylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules and novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling: A key reagent for forming carbon-carbon bonds between aryl/benzyl groups and various aryl halides or triflates, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a versatile synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific benzyl-substituted structures.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology Probes: Useful for creating tagged molecules or inhibitors for studying biological pathways and protein functions.

Basic Information

Product Name	Benzylboronic Acid Pinacol Ester
CAS No.	87100-28-5
Molecular Formula	C₁₃H₁₉BO₂
Molecular Weight	218.10 g/mol
Synonyms	Benzylboronic Acid Pinacol Ester; Benzylboronic Acid Pinanediol Ester; (Benzylboronic Acid) Pinacol Ester; Pinacol Benzylboronate; Benzylboronic Acid, Pinacol Ester; 2-(Phenylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzyl Pinacol Boronate; B-Benzyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Benzylboronic Acid Pinacol Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade materials, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis and maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.