Description

Lysine Valproate is a stable, water-soluble salt form of the essential amino acid L-Lysine and the active pharmaceutical ingredient Valproic Acid. This compound is primarily engineered to enhance the bioavailability and stability of valproate-based therapeutics, offering a critical advantage in pharmaceutical formulation. It is a key intermediate and active ingredient for manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing advanced neurological and psychiatric medications.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in the formulation of anti-epileptic and mood-stabilizing medications.
• Neuropharmacology Research: Serves as a critical standard and reagent in preclinical and clinical research for studying seizure disorders and bipolar disorder mechanisms.
• Drug Delivery Systems: Utilized in the development of improved delivery platforms, such as sustained-release formulations, to enhance patient compliance and therapeutic outcomes.
• Reference Standard: Used in quality control laboratories as a high-purity chemical reference standard for assay calibration and method validation.
• Intermediate for Prodrug Synthesis: Acts as a building block for creating more advanced prodrugs with targeted release profiles.

Basic Information

Product Name	Lysine Valproate
CAS No.	86827-89-6
Molecular Formula	C11H22N2O4
Molecular Weight	246.31 g/mol
Synonyms	L-Lysine valproate; Valproate lysine; Valproic acid lysine salt; 2,6-Diaminohexanoic acid compound with 2-propylpentanoic acid (1:1); Lysine 2-propylpentanoate; VPA-Lys; NSC 758842; L-Lysine, compd. with 2-propylpentanoic acid (1:1)
EINECS	Contact for details

Quality Control

Our Lysine Valproate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.