Description

2,6-Di-tert-Butyl-4-Methyl-D3-Phenol is a deuterated isotopologue of the widely used antioxidant butylated hydroxytoluene (BHT). This compound matters for researchers and manufacturers requiring precise metabolic and degradation pathway studies, as the deuterium labeling provides a non-radioactive isotopic tracer. It is primarily needed by the pharmaceutical, agrochemical, and material science industries for advanced analytical applications, including mass spectrometry and NMR spectroscopy, where tracking molecular fate is critical.

Application

• Metabolic Tracing in Pharmaceuticals: Used as a deuterium-labeled internal standard or tracer to study the absorption, distribution, metabolism, and excretion (ADME) of phenolic antioxidants and related compounds.
• Polymer & Material Science Research: Employed to investigate the mechanism, efficiency, and degradation products of antioxidant stabilization in plastics, rubbers, and fuels under controlled conditions.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for quantitative analysis via GC-MS or LC-MS in quality control and forensic laboratories.
• Mechanistic Studies in Agrochemicals: Utilized to trace the environmental degradation and transformation pathways of phenolic compounds used in formulations.
• Isotope Effect Research: Fundamental research tool for studying kinetic isotope effects (KIE) in oxidation and radical scavenging reactions.
• Synthesis of Labeled Derivatives: Acts as a key deuterated building block for the synthesis of more complex isotopically labeled molecules for research.

Basic Information

Product Name	2,6-Di-tert-Butyl-4-Methyl-D3-Phenol
CAS No.	86819-59-2
Molecular Formula	C15H21D3O
Molecular Weight	223.37 g/mol
Synonyms	2,6-Di-tert-butyl-4-(methyl-d3)phenol; Deuterated BHT; BHT-d3; 2,6-Bis(1,1-dimethylethyl)-4-(methyl-d3)phenol; 4-Methyl-D3-2,6-di-tert-butylphenol; Butylated Hydroxytoluene-d3; DBPC-d3; 3,5-Di-tert-butyl-4-hydroxy-D3-toluene; Antioxidant 264-d3
EINECS	Contact for details

Quality Control

Our 2,6-Di-tert-Butyl-4-Methyl-D3-Phenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and Mass Spectrometry for isotopic purity and structural confirmation, and HPLC for chemical purity assessment. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residues. Our quality commitment ensures the material meets the stringent requirements for research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Melting Point	69 - 71 °C
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.