Description

2-Amino-4-(4-Methylphenyl)Thiophene-3-Carbonitrile is a high-value heterocyclic organic building block characterized by its amino and nitrile functional groups on a thiophene core. This compound matters as a versatile and critical intermediate in the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and pigments, where the aminothiophene structure contributes to color properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex molecular libraries.

Basic Information

Product Name	2-Amino-4-(4-Methylphenyl)Thiophene-3-Carbonitrile
CAS No.	86604-37-7
Molecular Formula	C12H10N2S
Molecular Weight	214.29 g/mol
Synonyms	2-Amino-4-(p-tolyl)thiophene-3-carbonitrile; 4-(4-Methylphenyl)-2-aminothiophene-3-carbonitrile; 2-Amino-4-(4-methylphenyl)-3-thiophenecarbonitrile; 3-Cyano-2-amino-4-(4-methylphenyl)thiophene; 2-Amino-4-(4'-methylphenyl)thiophene-3-carbonitrile; 2-Amino-4-(p-methylphenyl)-3-thiophenecarbonitrile; 2-Amino-4-(4-tolyl)thiophene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Methylphenyl)Thiophene-3-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.