Description

8-Methyl-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one is a specialized heterocyclic organic compound belonging to the benzazepinone class, serving as a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique fused ring structure, which provides a versatile scaffold for constructing complex molecules with targeted biological activity. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical synthesis laboratories for the development of novel active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Organic Synthesis Scaffold: Utilized as a versatile core structure for constructing complex heterocyclic compounds and libraries for medicinal chemistry and high-throughput screening.
• Chemical Research & Development: Serves as a critical reagent in academic and industrial R&D settings for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other performance materials requiring a benzazepinone motif.

Basic Information

Product Name	8-Methyl-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
CAS No.	86499-66-3
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	8-Methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one; 8-Methyl-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one; 2H-1-Benzazepin-2-one, 1,3,4,5-tetrahydro-8-methyl-; 8-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-2-one
EINECS	Contact for details

Quality Control

Our 8-Methyl-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. All products undergo rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.