Description

1H-Pyrrolizine-1-Carboxaldehyde, Hexahydro-5-Oxo- (9Ci) is a specialized heterocyclic building block with a fused pyrrolizine core and an aldehyde functional group. This compound is valued for its unique molecular scaffold, which serves as a critical intermediate in the synthesis of complex pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, leveraging its reactive aldehyde group for further functionalization (e.g., condensation, reduction, nucleophilic addition).
• Agrochemical Research: Potential intermediate in the development of new pesticides or herbicides, utilizing its heterocyclic structure.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development and exploration of new chemical spaces in both academic and corporate research laboratories.

Basic Information

Product Name	1H-Pyrrolizine-1-Carboxaldehyde, Hexahydro-5-Oxo- (9Ci)
CAS No.	86486-10-4
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Hexahydro-5-oxo-1H-pyrrolizine-1-carboxaldehyde; 1H-Pyrrolizine-1-carboxaldehyde, hexahydro-5-oxo-; 1-Formylhexahydro-5-oxo-1H-pyrrolizine; 1-Carboxaldehydehexahydro-5-oxo-1H-pyrrolizine; 5-Oxohexahydro-1H-pyrrolizine-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizine-1-Carboxaldehyde, Hexahydro-5-Oxo- (9Ci) is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We support cGMP-compliant production for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.