Description

Purine-6-Sulfenic Acid is a specialized, high-purity biochemical intermediate of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters for its role as a key building block in the development of novel nucleoside analogs and potential therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on purine chemistry, antiviral drug discovery, and enzyme inhibitor studies.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel purine-based nucleoside analogs and prodrugs.
• Biochemical Research: Used in studies investigating sulfur-containing purine derivatives and their interactions with enzymes.
• Antiviral Drug Discovery: Serves as a precursor in the research and development of potential antiviral and anticancer agents.
• Organic Synthesis: A valuable reagent for introducing the sulfenic acid functional group into complex molecular architectures.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Enzyme Inhibitor Studies: Utilized in biochemical assays to study the mechanism of action of purine-metabolizing enzymes.

Basic Information

Product Name	Purine-6-Sulfenic Acid
CAS No.	86335-59-3
Molecular Formula	C5H4N4OS
Molecular Weight	168.17 g/mol
Synonyms	6-Sulfenylpurine; Purine-6-thial S-oxide; 1H-Purine-6-sulfenic acid; 6-Purinesulfenic acid; 9H-Purine-6-sulfenic acid; 6-Mercaptopurine S-oxide; NSC 401024; AI3-52522
EINECS	Contact for details

Quality Control

Our Purine-6-Sulfenic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, the container should be kept sealed and allowed to reach ambient temperature before opening to minimize moisture ingress and oxidative degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.