Description

Benzothiazole, 2,3-Dihydro-3-Acetyl-2-(5-Methoxy-2-(4-(4-(2-(3,4,5-Tri Methoxyphenyl)Ethyl)-1-Piperazinyl)Butoxy)Phenyl)-, Dihydrochloride is a complex, high-purity organic salt of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for investigating novel therapeutic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on central nervous system (CNS) agents or other specialized receptor-targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, particularly for CNS applications.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies to investigate receptor binding and signal transduction mechanisms.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale under current Good Manufacturing Practice (cGMP) conditions.
• Analytical Standard: Provides a high-purity benchmark for developing and validating analytical methods such as HPLC, LC-MS, and NMR for quality control.
• Preclinical Studies: Utilized in the formulation of compounds for in vitro and in vivo efficacy and toxicity screening.
• Custom Synthesis: Acts as a starting material for the preparation of derivatives and analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Benzothiazole, 2,3-Dihydro-3-Acetyl-2-(5-Methoxy-2-(4-(4-(2-(3,4,5-Tri Methoxyphenyl)Ethyl)-1-Piperazinyl)Butoxy)Phenyl)-, Dihydrochloride
CAS No.	86135-92-4
Molecular Formula	C35H44N2O6S · 2HCl
Molecular Weight	689.71 g/mol (Free base: 620.80 g/mol)
Synonyms	2,3-Dihydro-3-acetyl-2-[5-methoxy-2-[4-[4-[2-(3,4,5-trimethoxyphenyl)ethyl]-1-piperazinyl]butoxy]phenyl]benzothiazole dihydrochloride; 2-(5-Methoxy-2-(4-(4-(2-(3,4,5-trimethoxyphenyl)ethyl)piperazin-1-yl)butoxy)phenyl)-3-acetyl-2,3-dihydrobenzothiazole dihydrochloride; 86135-92-4; Benzothiazole derivative dihydrochloride salt; Compound 86135-92-4; Potential CNS agent intermediate; Research benzothiazole piperazine derivative.
EINECS	Contact for details

Quality Control

Our Benzothiazole derivative dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.