Description

3-(Trifluoromethyl)Thiophene is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is prized for its ability to introduce the metabolically stable and lipophilic trifluoromethyl group into complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of conductive polymers, organic semiconductors, and liquid crystals for electronic and optoelectronic devices.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, facilitating more efficient and selective chemical transformations.
• Fluorine Chemistry Research: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and the properties of fluorinated compounds.

Basic Information

Item	Detail
Product Name	3-(Trifluoromethyl)Thiophene
CAS No.	86093-77-8
Molecular Formula	C5H3F3S
Molecular Weight	152.14 g/mol
Synonyms	3-(Trifluoromethyl)thiophene; α,α,α-Trifluoro-m-toluenethiol; 3-Trifluoromethylthiophene; 3-Thienyltrifluoromethane; Thiophene, 3-(trifluoromethyl)-; 86093-77-8; 3-CF3-Thiophene
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its sensitivity to fluoride/strong alkali, isolate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.