Description

1H-Indole-2-Sulfonyl Chloride, 1-(Phenylsulfonyl)- is a specialized sulfonyl chloride derivative of indole, serving as a high-value synthetic intermediate. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel sulfonamide-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting enzyme inhibition via sulfonamide groups.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that incorporate sulfonyl moieties for enhanced bioactivity.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and target engagement.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Organic Synthesis Building Block: Facilitates the introduction of the sulfonyl chloride functional group into complex indole structures for further derivatization.

Basic Information

Item	Details
Product Name	1H-Indole-2-Sulfonyl Chloride, 1-(Phenylsulfonyl)-
CAS No.	85953-39-5
Molecular Formula	C14H10ClNO4S2
Molecular Weight	355.82 g/mol
Synonyms	1-(Phenylsulfonyl)-1H-indole-2-sulfonyl chloride; 1-(Benzenesulfonyl)-1H-indole-2-sulfonyl chloride; 1H-Indole-2-sulfonyl chloride, 1-(phenylsulfonyl)-; N-(Phenylsulfonyl)indole-2-sulfonyl chloride; 1-Benzenesulfonylindole-2-sulfonyl chloride; 85953-39-5; 1-Phenylsulfonylindole-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Sulfonyl Chloride, 1-(Phenylsulfonyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.