Description

2-Benzothiazolemethanamine,n-2-Propynyl-(9Ci) is a specialty heterocyclic amine derivative featuring a benzothiazole core linked to a propargylamine moiety, widely employed as a key building block in pharmaceutical and agrochemical synthesis. Its structural uniqueness enables selective functionalization for the development of bioactive molecules with enhanced potency and metabolic stability. This compound is critically valued by R&D chemists and process engineers in pharmaceutical intermediates, agrochemical active ingredient synthesis, and advanced materials research. It is supplied under strict quality controls to ensure batch-to-batch reproducibility and regulatory compliance.

Application

• Intermediate in the synthesis of benzothiazole-based kinase inhibitors and antiviral agents
• Building block for novel fungicides and herbicidal compounds targeting plant-specific metabolic pathways
• Reagent in copper-catalyzed azide–alkyne cycloaddition (CuAAC) for bioconjugation and PROTAC linker development
• Key precursor in the manufacture of high-performance corrosion inhibitors for industrial lubricants and metalworking fluids
• Substrate for radiolabeling studies (e.g., 11C or 18F incorporation) in PET tracer development
• Functional monomer in conductive polymer synthesis for organic electronics and sensor applications

Basic Information

Product Name	2-Benzothiazolemethanamine,n-2-Propynyl-(9Ci)
CAS No.	85902-44-9
Molecular Formula	C11H9N3S
Molecular Weight	215.27 g/mol
Synonyms	N-(Prop-2-ynyl)-2-(aminomethyl)benzothiazole; N-Propargyl-2-aminomethylbenzothiazole; 2-(Aminomethyl)-N-(prop-2-ynyl)benzothiazole; 2-Benzothiazolylmethyl(propargyl)amine; Propargyl(2-benzothiazolylmethyl)amine; NSC 642312; ZINC000013377285; AKOS025953254
EINECS	Not listed (not pre-registered under REACH as of 2024)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to ACS Reagent Grade specifications for identity, purity, and impurity profiling, and are manufactured under ISO 9001:2015-certified processes. Testing includes full spectral verification (IR, 1H-NMR), assay quantification (HPLC), residual solvent analysis (GC), and heavy metals screening (USP <231>).

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity; use desiccant during storage and handling. Avoid contact with strong oxidizing agents and acidic vapors.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard spectrum
Identification (1H-NMR)	Conforms to reference standard spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Each impurity ≤ 0.3%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C Class 3 limits
Water (Karl Fischer)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.