Description

Pirlimycin Adenylate CAS NO 85643-04-5 is a key nucleotide derivative of the lincosamide antibiotic pirlimycin. This compound is primarily valued as a critical intermediate in the synthesis and research of advanced antibacterial agents. It is essential for pharmaceutical R&D teams, academic researchers, and manufacturers focused on developing novel therapeutics targeting Gram-positive bacterial infections. Its role is pivotal in studying antibiotic mechanisms and creating new formulations.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of Pirlimycin hydrochloride, a veterinary antibiotic for mastitis treatment.
• Antibacterial Research: Serves as a crucial reference standard and building block in microbiological and biochemical studies of lincosamide antibiotics.
• Veterinary Drug Development: Used in R&D for formulating new intramammary infusions and other delivery systems for livestock.
• Mechanistic Studies: Employed to investigate the mode of action, resistance mechanisms, and structure-activity relationships (SAR) of antibiotics.
• Analytical Standard: Acts as a high-purity standard for quality control (QC) and assay development in pharmaceutical manufacturing.
• Bioconjugation & Prodrug Synthesis: Utilized in creating targeted drug delivery systems and prodrug candidates to enhance therapeutic efficacy.

Basic Information

Item	Detail
Product Name	Pirlimycin Adenylate
CAS No.	85643-04-5
Molecular Formula	C26H39N7O10P
Molecular Weight	640.61 g/mol
Synonyms	Pirlimycin 5'-Adenylic Acid; Pirlimycin Adenylate Ester; U-57930E; Adenosine 5'-(Pirlimycin Dihydrogen Phosphate); 5'-O-[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinecarbonyl]adenosine Dihydrogen Phosphate; Pirlimycin-AMP; Pirlimycin Adenosine Monophosphate
EINECS	Contact for details

Quality Control

Our Pirlimycin Adenylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.