Description

3-Nitrothiophene-2-Carbonitrile is a high-purity, specialized heterocyclic building block with significant synthetic utility. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its nitro and nitrile functionalities.
• Material Science Research: Serves as a building block for creating conjugated polymers and organic electronic materials due to the thiophene backbone.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and functional colorants.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke fine chemicals and advanced intermediates for client-specific projects.

Basic Information

Product Name	3-Nitrothiophene-2-Carbonitrile
CAS No.	85598-51-2
Molecular Formula	C5H2N2O2S
Molecular Weight	154.15 g/mol
Synonyms	2-Cyano-3-nitrothiophene; 3-Nitro-2-thiophenecarbonitrile; 3-Nitrothiophene-2-carbonitrile; Thiophene-2-carbonitrile, 3-nitro-; 2-Thiophenecarbonitrile, 3-nitro-; 3-Nitro-2-cyanothiophene; 3-Nitrothieno[2,3-c]pyridine precursor
EINECS	Contact for details

Quality Control

Our 3-Nitrothiophene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, confirming compliance with customer and research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.